A composition of solid protein-containing waste of fur production is investigated and it is established that a high content of an offal substance and a comparatively low contentof unbound fatty substances make processing the waste formed during fleshing skins of bear, sheepskins, and deer foots into the protein hydrolysate more reasonable.Based on the found data on the chemical composition of the feedstock, the technology of fabrication of alkali protein hydrolysate applying sodium hydroxide is proposed.Low-molecular dissolution products of collagen with satisfactory colloid-chemical properties are fabricated, notably, sufficient wetting, emulsifying, foaming, and washingabilities. Production parameters of performing coaking of fur sheepskin with applying biosurfactants, which made it possible to exclude the application of synthetic surfactantsand antiseptics, are developed. This was resulted in the fabrication of a semifinished product, the quality of which corresponds to the standard, and a decrease in toxicityof discharges by a factor of 17.4 is established. The proposed complex solution makes it possible to reduce the amount of solid collagen-containing waste by means oftheir processing into biosurfactants and reduce the toxicity of liquid waste due to the replacement of synthetic surfactants by developed biosurfactants in soaking productionprocesses of fur sheepskin.